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Faculty Merit Postdoctoral Professional & Scientific Research Temporary Internal

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Requisition # 2861

Position Basics

Advertising Ends on:Tuesday, November 30th, 1999
Advertising Started on:Tuesday, September 12th, 2017
College:Carver College of Medicine
Department:Wynn Inst Vision Rsch


Salary:$47,484.00 - $58,560.00

Position Details

Full/Part Time Status:Full Time
Percent Time:100%
Position Description:

A Postdoctoral Scholar position is available immediately at the Wynn Institute for Vision Research, Department of Ophthalmology and Visual Sciences. The research position is focused on i) Stem cell biology, ii) Gene therapy, & iii) CRISPR based genome editing as means to treat rare inherited eye disease. The laboratory employs genetic rat and pig models of disease, and human iPSC culture systems, as well as multidisciplinary approaches ranging from Molecular Biology to Biochemistry, Cell Biology, and Proteomics. Applicants should have solid conceptual and research background in molecular and cellular biology with an excellent publication record. Individuals who are highly motivated and willing to take risks for innovation are encouraged to apply. The successful candidate is expected to work independently, yet in a collaborative environment with a group of scientists with various expertise.



-Work independently on basic research tasks with oversight by Principal Investigator (PI).

-Investigate pathophysiological mechanisms of photoreceptor degeneration associated with specific gene defects using human cell culture systems.

-Conduct molecular, biochemical and cell biological experiments to elucidate molecular functions of newly identified disease causing genes.

-Develop novel gene based approaches for the treatment of inherited eye disease.

-Collect and analyze experimental data and evaluate relevance of the data.

-Compare experimental data with published work and develop and test new hypotheses.

-Contribute to documentation of equipment and procedures.

-Supervise and collaborate with graduate students and other members of the laboratory


Dissemination of Research Results

-Prepare manuscripts for publication. 

-Present results in departmental seminars and at scientific meetings.


Research Proposals/Grants

-Contribute to new or continuing research grant proposals to obtain funding for research activities. 

-Contribute to progress reports required by funding agencies. 

-Supervise adherence to safety and compliance guidelines when necessary.


Education Requirement:

A PhD or MD/PhD degree in Biological Sciences

Required Qualifications:

  • 4-6 years of hands-on research experience in cell culture and molecular and cellular biology but less than 4 years of post-PhD experience.

  • Proficient in standard molecular biology techniques (e.g. cloning, site-directed mutagenesis, and RT-PCR, DNA and RNA isolation, quantitative Real Time PCR, RNA interference), common biochemical techniques (e.g. expression and purification of recombinant proteins, protein isolation and purification from human and mouse tissue samples, SDS-PAGE, immunoblotting and densitometric analysis), common cell biology techniques (e.g. immunofluorescence) and tissue culture techniques (i.e. establishing and maintaining primary cell lines and generating stable cell lines).

  • Excellent oral, written, and interpersonal skills.

Online Application Required Documents

 Curriculum Vita
Name and Contact Information of References
Letters of Interest
 Number of References:  3

To start the Online Application process for this position, click the "Apply for This Position" button located below the Contact Information.

Contact Information

Contact:Luan M Streb -
Cmed-Wynn Inst Vision Rsch
4111 MERF
Phone: 319-335-8270

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